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Affiliations:

UMCES

Carys Mitchelmore Profile Page
Carys Mitchelmore

Additional Info

Bernie Fowler Lab
Associate Professor
(410) 326-7283
(410) 326-7270
(410) 326 7210
Environmental Chemistry/Toxicology

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Contact Info

Carys Mitchelmore
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Education

1997; PhD Toxicity in Aquatic Organisms; University of Birmingham, School of Biochemistry in collaboration with Plymouth Marine Laboratory, U.K. 1993; MSc Applied Toxicology; University of Portsmouth, U.K. In association with GlaxoWellcome, Dept. Immunotoxicology, Ware, U.K. 1992; BSc (Hons) Biology, University of Portsmouth, U.K.

Interests

Aquatic Toxicology; Investigating molecular, biochemical and cellular responses of aquatic organisms to inorganic and organic pollutants.

Professional Experiences

Please see people section on the Mitchelmore lab website to download my CV.

Recent Publications

Peer-Reviewed Publications (papers, book chapters and books) 2005 National Research Council (NRC). 2005. Oil Spill Dispersants: Efficacy and Effects. National Academies Press, Washington, D.C. 2004 Mitchelmore, C.L. and Hyatt, S. (2004). Assessing DNA damage in cnidarians using the Comet Assay. Mar. Environ. Res., 58, 707-711. 2003 Mitchelmore, C.L., Verde, E.A., Ringwood, A.H. and Weis, V.M. (2003). Differential accumulation of heavy metals in the sea anemone Anthopleura elegantissima as a function of symbiotic state. Aquat. Toxicol., 64, 3, 317-2. Mitchelmore, C.L., Ringwood A.H. and Weis V.M. (2003). Differential accumulation of cadmium and changes in glutathione levels as a function of symbiotic state in the sea anemone Anthopleura elegantissima. JEMBE, 284, 71-85. 2002 Mitchelmore, C.L., Schwarz, J.A. and Weis, V.M. (2002). Development of symbiosis-specific genes as biomarkers for the early detection of cnidarian-algal symbiosis breakdown. Mar. Environ. Res., 54, 345-349. 2001 Doyotte A., Mitchelmore, C.L., Ronisz, D., McEvoy, J., Livingstone, D.R. and Peters, L.D. (2001). Hepatic 7-ethoxyresorufin O-dethylase activity in eel (Anguilla anguilla) from the Thames Estuary and comparisons with other United Kingdom estuaries. Mar. Pollut. Bull., 42, 12, 1313-1322. Peters L.D., Doyotte, A., Mitchelmore C.L., McEvoy J. and Livingstone, D.R. (2001). Seasonal variation and estradiol-dependent elevation of Thames Estuary eel Anguilla anguilla plasma vitellogenin levels and comparisons with other United Kingdom estuaries. Science of the Total Environment, 279, 137-150. 2000 Livingstone D.R., Chipman J.K., Lowe D.M., Mitchelmore C.L., Moore M.N., Peters L.D. and Pipe R.K. (2000). Development of biomarkers to detect the effects of organic pollution on aquatic invertebrates: recent molecular, genotoxic, cellular and immunological studies on the common mussel (Mytilus edulis L.) and other mytilids. Int. J. Environ. Pollut., 13, 56-91. Livingstone D.R., Mitchelmore C.L., OÕHara S.C.M., Lemaire P., Sturve J. and Forlin L. (2000). Increased Potential for NAD(P)H-dependent Reactive Oxygen Species Production of Hepatic Subcellular Fractions of Fish Species with In Vivo Exposure to Contaminants. Mar. Environ. Res., 50, 57-60. Livingstone D.R., Mitchelmore C.L., Peters L.D., OÕHara S.C.M., Shaw J., Chesman B., Doyotte A., McEvoy J., Ronisz D., Larsson D.G.J. and Forlin L. (2000). Development of Hepatic CYP1A and Blood Vitellogenin in Eel (Anguilla anguilla) for Use as Biomarkers in the Thames Estuary, UK. Mar. Environ. Res., 50, 367-371. Pre-2000 Mitchelmore C.L. and Chipman J.K. (1998). DNA strand breakage in aquatic organisms and the potential value of the comet assay in environmental monitoring. Mutation Res., 399, 135-147. Mitchelmore C.L. and Chipman J.K. (1998). Detection of DNA strand breaks in Brown Trout Salmo trutta) hepatocytes and blood cells using the single cell gel electrophoresis (comet) assay. Aquat. Toxicol., 41, 1-2, 161-182. Mitchelmore C.L., Birmelin C., Livingstone D.R. and Chipman J.K. (1998). Evidence for cytochrome P450 catalysis and free radical involvement in the production of DNA strand breaks by benzo[a]pyrene and nitroaromatics in mussel (Mytilus edulis L.) digestive gland cells. Aquat. Toxicol., 41, 3, 193-212. Mitchelmore C.L., Birmelin C., Livingstone D.R. and Chipman J.K. (1998). Detection of DNA strand breaks in isolated mussel (Mytilus edulis L.) digestive gland cells using the comet assay. Ecotox. Environ. Safety, 41, 51-58. Mitchelmore C.L., Livingstone D.R. and Chipman J.K. (1998). Conversion of 1-nitropyrene by Brown trout (Salmo trutta) and turbot (Scophthalamus maximus) to DNA adducts detected by 32P-postlabelling. Biomarkers, 3, 1, 21-33. Birmelin C., Mitchelmore C.L. Goldfarb P.S. and Livingstone D.R. (1998). Characterisation of biotransformation enzyme activities and DNA integrity in isolated cells of digestive gland of the common mussel, Mytilus edulis L. Comp. Biochem. Physiol.,120, 1, 51-56.